Structure Dynamics-Guided Biocatalyst Improvement
| 项目名称： | Structure Dynamics-Guided Biocatalyst Improvement |
| 摘要： | The success in the proposed research will open a new chapter in biocatalyst improvement and greatly benefit the biorefinery industry with three folds. First, the project team will deliver a novel platform using Hydrogen Deuterium Exchange (HDX) mass spectrometry for biocatalyst improvement, and the platform can be used for enzyme improvement of various purposes. Second, the team will be able to deliver some biocatalysts with higher efficiency and better inhibitor resistance. These biocatalysts will help to improve the biorefinery procedure and biomass conversion efficiency tremendously. Third, the proposed research will help to elucidate the molecular mechanisms for the cellulase enzyme catalysis and inhibition from the dynamic perspectives, which will guide the future enzyme improvement. |
| 状态： | Completed |
| 资金： | 63436.00 |
| 资助组织： | Research and Innovative Technology Administration |
| 项目负责人： | Johnson, Shawn |
| 执行机构： | Texas A&M University, College Station |
| 开始时间： | 20090701 |
| 实际结束时间： | 20110630 |
| 主题领域： | Energy；Transportation (General) |
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