原文传递 Interpretation of Carboxyhemoglobin and Cyanide Concentrations in Relation to Aviation Accidents. Final rept.
题名: Interpretation of Carboxyhemoglobin and Cyanide Concentrations in Relation to Aviation Accidents. Final rept.
作者: CANFIELD, D. V.; CHATURVEDI, A. K.; DUBOWSKI, K. M.
关键词: *Aviation-accidents; *Cyanides-; *Carboxyhemoglobin-; *Carbon-monoxide.;Toxicity-; Death-; Combustion-products; Gases-; Fires-; Exposure-; Humans-; Toxic-hazards; Prevention-.
摘要: Carbon monoxide poisoning has been the cause of death in humans since the first human discovered the use of fire for warmth, protection, and cooking. It continues today as a cause of death in humans. The introduction of household products containing synthetic nitrogenous materials in the early 19th century has increased the chance of hydrogen cyanide (a toxic combustion gas) production in a fire. The Civil Aerospace Medical Institute (CAMI) became directly involved in combustion toxicology in 1970, when a Capitol International Airways DC-8 aircraft crashed on takeoff at Anchorage, Alaska, and blood specimens from the victims were found to contain cyanide (CN) inhaled during the post-crash fire. The Federal Aviation Administration (FAA), as well as the public, wanted to know the source of the cyanide and what could be done to prevent a recurrence of cyanide exposures. At that time, little was known about the potential for aircraft interior materials to produce toxic combustion gases. Even more surprising was the lack of documented data on the toxicity of individual combustion gases. During the ensuing years, scientists at the FAA Technical Center and CAMI have systematically researched this issue to answer some important questions.
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