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原文传递 Multiple Medications and Vehicle Crashes: Analysis of Databases.

题名：	Multiple Medications and Vehicle Crashes: Analysis of Databases.
作者：	leroy, a. a. pharm, d. morse, m. l.
关键词：	crashes, driving, impairing effects, data bases
摘要：	The number of older adults is expected to increase dramatically in the next 25 years and with it, an increase in both the number of older drivers and the amount of driving within this age group. With the aging of the American population, concern arises regarding potential increases in rates of crash involvement and injury. Age-related factors may impair driving ability, such as age-related decrements in cognitive and physical functioning, increased prevalence of medical conditions or age-related medical conditions, and increased use of multiple medications. Using population databases, this study analyzed the association of the impairing effects of multiple medication use, drug interactions, and drug disease interactions on motor vehicle crashes (MVC) in individuals age 50 years and greater. Methodology: The main objectives of this study were to determine the relative frequency of various combinations of medications used by those who have experienced a MVC and those who have not by analyzing proprietary and non-proprietary databases; and to conduct a case-control study of possible associations between the use of medications (and combinations thereof) and MVCs amongst older drivers. / NOTE: Final rept. Sep 02-05 Sep. / Supplementary Notes: Sponsored by National Highway Traffic Safety Administration, Washington, DC. and Department of Transportation, Washington, DC. / Availability Note: Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA.
总页数：	u0824；261p
报告类型：	科技报告