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Validating Epigenetic and Genetic Biomarkers for Diagnosis of Bladder Pain of Interstitial Cystitis.
| 题名： | Validating Epigenetic and Genetic Biomarkers for Diagnosis of Bladder Pain of Interstitial Cystitis. |
| 作者： | Kim, J. |
| 摘要： | The goal of this study is to determine the biosignature consisting of DNAmethylation and gene expression status detected in urine from interstitialcystitis/painful bladder syndrome (IC) patients will stratify IC patientsfrom healthy controls. In this funding year, we have focused on (1)identification on baseline of urine collection, (2) expansion of databasefor better urine biomarker discovery, and (3) technology application tofurther identify the DNA methylation markers associated with IC. Inparticular, we were able to optimize the DNA methylation and gene expressionassays, which were designed for high-throughput screening (HTS). |
| 总页数： | 183 pages |
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