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Characteristics and oxidative stress on traffic policemen of ambient fine particulate matter from Shenyang
| 题名： | Characteristics and oxidative stress on traffic policemen of ambient fine particulate matter from Shenyang |
| 正文语种： | 中文 |
| 作者： | Mingyue Ma Shuyin Li Huanrong Jin Yumin Zhang Jia Xu ongmei Chen Kuimin Chen Yuan Zhou Chunling Xiao |
| 作者单位： | epartment of Toxicology,School of Public Health,Shenyang Medical ollege |
| 关键词： | Fine particulate matter Traffic policemen DNA damage oxidative stress |
| 摘要： | This study aimed to investigate the adverse health effects of fine particulate matter (PM 2.5) from Shenyang.The concentration and composition of PM2.5 in traffic policemen's working sites including fields and indoor offices were obtained.Blood samples of field and offices policemen were collected to detect DNA damage by Comet assay.And the logistic regression analysis of the factors affecting the DNA damage was carried out.Characteristics of samples collected during the winter and summer differ significantly.The percentage of comet cell in exposed group had no obvious difference with control group.After grading the damaged cells, the percentage of level 3 damaged comet cells was significantly higher than those in control group.But no significant correlation with age or length of service was found.Moreover, animal studies confirmed the oxidative DNA damage induced by ambient PM 2.5. |
| 会议日期： | 20150922 |
| 会议举办地点： | 沈阳 |
| 会议名称： | 第九届中日国际环境与健康学术研讨会暨辽宁省第七次微生态学学术研讨会暨委员会议 |
| 出版日期： | 2015-09-22 |
| 母体文献： | 第九届中日国际环境与健康学术研讨会暨辽宁省第七次微生态学学术研讨会暨委员会议论文集 |
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